3/22/2021 0 Comments Cml And Sml
If youre like most folks, youve got a general idea of what the term means, but you may be fuzzy on the details.For CML, also called chronic myeloid leukemia, there are some concrete milestones that you need to reach.Roboz, MD, director of the Leukemia Program at Weill Cornell Medical College in New York City.But actually in CML there are specific categories of remission.
It means your blood cell count is back to normal and tests dont show any abnormal white blood cells. Also, if your spleen was swollen, its now at its original size. Youve reached this milestone when your blood or bone marrow -- the inside of your bone where blood cells are made -- no longer has any cells with the Philadelphia chromosome. Thats the one that carries a gene called BCR-ABL, which plays a role in the process that creates abnormal white blood cells. Mauro, MD, of Memorial Sloan Kettering Cancer Center in New York City. Thats when the leukemia is 1,000 times smaller than when we started. ![]() Your doctor will say youre in this category when the BCR-ABL gene doesnt show up in your blood. Doctors look for major molecular remission within the first year or two, and research is under way to see if its OK to stop treatment after youve been in it for a period of time. Thats a mistake patients make because they are worried, Roboz says. They see their white blood cell count go up at one visit, but it might just be they caught a cold from their kids and their white blood cell count is responding normally. But it is not true that a relapse is definitely devastating news. There are plenty of patients who will be switched to a different CML medication and do extremely well. WebMD does not provide medical advice, diagnosis or treatment.
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